General Cell Based Assays
Eurofins Discoverx PathHunter eXpress FGFR4-β-Klotho Functional Assay, 10pl Kit. (93-1060E3CP0L)
The PathHunter eXpress FGFR4-β-Klotho Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated FGFR4 and β-Klotho dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged FGFR4 and an EA-tagged SH2 domain protein. It also overexpresses an untagged coreceptor, β-Klotho. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter FGFR4-β-Klotho Bioassay Kit, 2pl. (93-1060Y3-00089)
The PathHunter FGFR4-β-Klotho Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses FGF19-induced activation of FGFR4-β-Klotho RTK receptors via detection of SH2 domain protein recruitment. The included cell line overexpresses ProLink-tagged FGFR4 and an EA-tagged SH2 domain protein. It also overexpresses an untagged coreceptor, β-Klotho. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Cell Signaling Technology Glucose-6-Phosphate Dehydrogenase (G6PD) Activity Assay Kit 1 Kit
Glucose-6-Phosphate Dehydrogenase (G6PD) Activity Assay Kit 1 Kit
Revvity Health Sciences Inc HTRF Human & Mouse Total c-Src Detection Kit, 50,000 Assay Points
HTRF Human & Mouse Total c-Src Detection Kit, 50,000 Assay Points
Revvity Health Sciences Inc HTRF Human Phospho-AKT1 (Ser473) Detection Kit, 500 Assay Points
HTRF Human Phospho-AKT1 (Ser473) Detection Kit, 500 Assay Points
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-VASP (Ser239) Detection Kit, 500 Assay Points
HTRF Human & Mouse Phospho-VASP (Ser239) Detection Kit, 500 Assay Points
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-VASP (Ser239) Detection Kit, 50,000 Assay Points
HTRF Human & Mouse Phospho-VASP (Ser239) Detection Kit, 50,000 Assay Points
Revvity Health Sciences Inc HTRF CD64 Cellular Binding Kit, 100 Assay Points
HTRF CD64 Cellular Binding Kit, 100 Assay Points
Eurofins Discoverx PathHunter eXpress EDG4 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0255E2CP13M)
The PathHunter EDG4 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. LPA) based activation of EDG4 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged EDG4 and EA-tagged β-Arrestin-2. Activation of EDG4 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Human Phospho-STAT5 (Tyr694) Detection Kit, 50,000 Assay Points
HTRF Human Phospho-STAT5 (Tyr694) Detection Kit, 50,000 Assay Points
Eurofins Discoverx PathHunter eXpress GCGR CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0241E2CP0L)
The PathHunter GCGR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. glucagon) based activation of GCGR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GCGR and EA-tagged β-Arrestin-2. Activation of GCGR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress F2RL1 (PAR2; GPR11) U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0235E3CP0M)
The PathHunter F2RL1 (PAR2; GPR11) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. proteases, SLIGRL) based activation of F2RL1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged F2RL1 and EA-tagged β-Arrestin-2. Activation of F2RL1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Bioss Actin Fruit Fly Loading Cont
Actin (Fruit Fly Loading Control) Primary Antibody Unconjugated Host Species Rabbit Target Species Clonality Monoclonal Applications WB Concentration 1mg/ml Size 100 ul Storage Buffer 0 01M TBS(pH7 4) with 1% BSA 0 02% Proclin300 and 50% Glycerol
Eurofins Discoverx PathHunter eXpress OXTR CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0261E2CP2M)
The PathHunter OXTR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. oxytocin) based activation of OXTR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged OXTR and EA-tagged β-Arrestin-2. Activation of OXTR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery U-PLEX Mouse IL-15 ASY
The Meso Scale Discovery U-PLEX Mouse IL-15 Assay Kit is designed for the quantitative measurement of mouse interleukin 15 (IL-15) in serum plasma cell culture supernatants cell and tissue lysates using an electrochemiluminescent detection technology The assay has high sensitivity and wide dynamic range It uses MSD GOLD SULFO-TAG labels and is compatible with MSD instrument platforms The kit includes a plate coated with capture antibody detection antibody calibrator diluent wash buffer and read buffer